Stem cells are one of the most fascinating fields in modern biology. They have important properties and serve as our body's repair kits.
What are stem cells?
Renewal and repair are ongoing processes in the human body. Adult stem cells supply the necessary cells for this replacement. They have been identified in over 20 organs or tissues. Two key features set them apart from ordinary cells: They can differentiate into a diverse range of specialized cells of the same tissue and they have the remarkable ability to renew and regenerate themselves through cell division throughout a person's life. This makes stem cells especially valuable and important in regenerative skin care research.
Stem cells in the skin – epidermal stem cells
Adult stem cells are also present in the outer layer of human skin, the epidermis. These cells are called epidermal stem cells and are found in the innermost layer of the epidermis (basal layer). Every second to seventh cell in this layer is a stem cell. Although their appearance does not differ from that of the other cells in the basal layer, stem cells have a unique function: They constantly renew and rejuvenate the epidermis by forming new keratinocytes and regenerate damaged tissue as only these cells have the ability to divide indefinitely (see figure).
In young skin, the epidermis fully renews itself approximately every 4 weeks. This process continuously slows as we age. The number of skin stem cells decreases and their vitality diminishes. Excessive UV exposure of the skin and an unhealthy lifestyle (smoking, alcohol) aggravate these effects considerably, resulting in thinner, more deeply wrinkled skin. The hydrolipid film is reduced, which leaves the skin dryer and less well protected. As no new epidermal stem cells can develop during a person's life, it is all the more important to maintain the vitality of these valuable cells and their ability to divide as long as possible. READ MORE
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